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Nakajima K, Takahashi K, Tanaka M, Kawashima M, Machida K, Nakao Y, Takubo K, *Goda N. Suppression of ATP-dependent (S)-NAD(P)H-hydrate dehydratase expression inhibits adipocyte differentiation of 3T3-L1 preadipocytes by increasing excessive accumulation of NADHX.
J Biochem. 2025 Mar 21:mvaf015. doi: 10.1093/jb/mvaf015. Online ahead of print.
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*Miyake N, Shiga K, Hasegawa Y, Iwabuchi C, Shiroshita K, Kobayashi H, Takubo K, Velilla F, Maeno A, Kawasaki T, Imai Y, Sakai N, Hirose T, Fujita A, Takahashi H, Okamoto N, Enokizono M, Iwasaki S, Ito S, *Matsumoto N. Biallelic TEDC1 variants cause a new syndrome with severe growth impairment and endocrine complications.
Eur J Hum Genet. 2025 Feb 20. doi: 10.1038/s41431-025-01802-3. Online ahead of print.
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Watanuki S, *Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, *Takubo K. SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Cell Stem Cell. 2024 May 14:S1934-5909(24)00176-0. doi: 10.1016/j.stem.2024.04.023. Online ahead of print.
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Karyu H, Niki T, Sorimachi Y, Hata S, Shimabukuro-Demoto S, Hirabayashi T, Mukai K, Kasahara K, Takubo K, Goda N, Honke K, Taguchi T, Sorimachi H, *Toyama-Sorimachi N. Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function.
Front Immunol. 2024 Apr 24;15:1401294. doi: 10.3389/fimmu.2024.1401294. eCollection 2024.
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Watanuki S, *Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, Oshima M, Nishiyama A, Murakami K, Haraguchi M, Tamaki S, Yamamoto T, Yabushita T, Tanaka Y, Nagamatsu G, Honda H, Okamoto S, Goda N, Tamura T, Nakamura-Ishizu A, Suematsu M, Iwama A, Suda T, *Takubo K. Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.
eLife. 2024 Apr 4;12:RP87674. doi: 10.7554/eLife.87674.
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Yahagi A, Mochizuki-Kashio M, Sorimachi Y, Takubo K, *Nakamura-Ishizu A. Abcb10 regulates murine hematopoietic stem cell potential and erythroid differentiation.
Exp Hematol. 2024 Jul;135:104191. doi: 10.1016/j.exphem.2024.104191. Epub 2024 Mar 15.
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*Awazawa M, Matsushita M, Nomura I, Kobayashi N, Tamura-Nakano M, Sorimachi Y, Takubo K, *Ueki K. Imeglimin improves systemic metabolism by targeting brown adipose tissue and gut microbiota in obese model mice.
Metabolism. 2024 Apr;153:155796. doi: 10.1016/j.metabol.2024.155796. Epub 2024 Jan 21.
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Iga T, Kobayashi H, Kusumoto D, Sanosaka T, Fujita N, Tai-Nagara I, Ando T, Takahashi T, Matsuo K, Hozumi K, Ito K, Ema M, Miyamoto T, Matsumoto M, Nakamura M, Okano H, Shibata S, Kohyama J, Kim KK, *Takubo K, *Kubota Y. Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis.
Nat Cell Biol. 2023 Oct;25(10):1415-1425. doi: 10.1038/s41556-023-01240-7. Epub 2023 Oct 5.
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*Takubo K, Htun PW, Ueda T, Sera Y, Iwasaki M, Koizumi M, Shiroshita K, Kobayashi H, Haraguchi M, Watanuki S, Honda Z, Yamasaki N, Nakamura-Ishizu A, Arai F, Motoyama N, Hatta T, Natsume T, Suda T, *Honda H. MBTD1 preserves adult hematopoietic stem cell pool size and function.
Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2206860120.doi:10.1073/pnas.2206860120. Epub 2023 Jul 31.
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Shiroshita K, Kobayashi H, Watanuki S, Karigane D, Sorimachi Y, Tamaki S, Haraguchi M, Yamamoto M, Nakamura-Ishizu A, Okamoto S, Kataoka K, *Takubo K. Distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells.
Exp Hematol. 2023 Jun 18:S0301-472X(23)00255-2.
