国立国際医療研究センター研究所 生体恒常性プロジェクト

英文原著論文

  • Hiroshi Kobayashi1, Takayuki Morikawa1, Ayumi Okinaga1, Fumie Hamano2, Tomomi Hashidate-Yoshida2, Shintaro Watanuki1,3, Daisuke Hishikawa2, Hideo Shindou2,6, Fumio Arai5, Yasuaki Kabe4, Makoto Suematsu4, Takao Shimizu2,7, Keiyo Takubo1. Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo.

    Cell Reports 2019 in press
  • Watanuki S, Kobayashi H, Sorimachi Y, Yamamoto M, Okamoto S, *Takubo K. ATP turnover and glucose dependency in hematopoietic stem/progenitor cells are increased by proliferation and differentiation.

    Biochem Biophys Res Commun.2019 Apr 25;514: 287-294.
  • Mima Y, Suzuki S, Fujii T, Morikawa T, Tamaki S, Takubo K, Shimoda M, Miyamoto T, Watanabe K, Matsumoto M, Nakamura M, *Fujita N. Potential involvement of semaphorin 3A in maintaining intervertebral disc tissue homeostasis.

    J Orthop Res. 2019 Feb 28;37:972-980.
  • Kobayashi H, Morikawa T, Okinaga A, Hamano F, Hashidate-Yoshida T, Watanuki S, Hishikawa D, Shindou H, Arai F, Kabe Y, Suematsu M, Shimizu T, *Takubo K. Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo.

    bioRxiv. 475905 [Preprint]. 2018 Dec 6;Available from: https://doi.org/10.1101/475905
  • Goto S, Morikawa T, Kubo A, Takubo K, Fukuda K, Kajimura M, Suematsu M. Quantitative imaging mass spectroscopy reveals roles of heme oxygenase-2 for protecting against transhemispheric diaschisis in the brain ischemia.

    J Clin Biochem Nutr. 2018 Jul ;63(1):70-79.
  • *Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, *Suda T.
    Folliculin regulates osteoclastogenesis through metabolic regulation.

    J Bone Miner Res. 2018 Jun 12;33:1785-1798.
  • Si S, Nakajima-Takagi Y, Iga T, Tsuji M, Hou L, Oshima M, Koide S, Saraya A, Yamazaki S, Takubo K, Kubota Y, *Minamino T, *Iwama A.
    Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.

    Exp Hematol. 2018 Apr 27;63:41-51.
  • Shiota M, *Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, *Suematsu M.
    Gold-nanofeve surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.

    Nat Commun. 2018 Apr 19;9(1):1561.
  • Iizuka-Hishikawa Y, Hishikawa D, Sasaki J, Takubo K, Goto M, Nagata K, Nakanishi H, Shindou H, Okamura T, Ito C, Toshimori K, Sasaki T, *Shimizu T. Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis.

    J Biol Chem. 2017 Jul 21;292(29):12065-12076.
  • *Tokumoto Y, Tamaki S, Kabe Y, Takubo K, Suematsu M. Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.

    Sci Rep. 2017 Apr 21;7(1):1019.